A small aircraft crashed on a street in Sao Paulo, Brazil’s largest city, killing at least two passengers, the local firefighter corps said in a statement.
The plane went down in the Barra Funda neighbourhood on the city’s west side.
A piece of the plane hit a bus, injuring one woman inside, while a motorcyclist was struck by another piece of wreckage, the statement said.
Both were receiving medical care.
A later statement said that four additional victims at the site were taken to hospitals in the region with minor injuries.
Images on local media showed the plane’s fuselage and the bus on fire, with firefighters working to extinguish the blaze.
The plane was bound for Porto Alegre, in the southern state of Rio Grande do Sul.
There was no word as to what had caused the plane to lose altitude and smash into the road less than three miles (five kilometres) from the private airport from which it had departed.