Israeli aircraft struck a sprawling tent camp housing displaced Palestinians in Gaza on Wednesday, killing at least 21 people, according to a local health official.

The attack set off fires in the coastal tent city that Israel has designated a humanitarian zone but which has been repeatedly targeted.

The Israeli military said it struck senior Hamas militants “involved in terrorist activities” in the area, without providing additional details, and said it took precautions to minimise harm to civilians.

The strikes were the latest deadly assault in the war-wracked Gaza Strip, where Israel’s offensive against Hamas is nearly 14 months old and showing no end in sight, despite international efforts to revive negotiations toward a ceasefire.

A Palestinian inspects the rubble of a destroyed building following an overnight Israeli strike in Deir al-Balah, Gaza Strip (Abdel Kareem Hana/AP)

The Biden administration has pledged to make a new push to get a ceasefire for Gaza after Israel and the Lebanese militant group Hezbollah agreed to end more than a year of cross-border fighting.

And President-elect Donald Trump demanded in a social media post this week the release of hostages held by Hamas before he is sworn into office in January.

The strike Wednesday in Muwasi, a desolate area with few public services that holds hundreds of thousands of displaced people, also wounded at least 28 people, according to Atif Al-Hout, the director of Nasser Hospital in the southern city of Khan Younis.

An Associated Press journalist at the hospital counted at least 15 bodies, but he said reaching a precise number was difficult because many of the dead were dismembered, some without heads or badly burned.

Videos and photos shared widely on social media showed flames and a column of black smoke rising into the night sky, as well as twisted metal tent frames and shredded fabric.

Palestinian men searched through the still-burning wreckage, shouting “Over here guys” Further away, civilians stood at a distance, observing the destruction.

The military said the strikes had set off secondary explosions, indicating explosives present in the area had detonated.

It was not possible to independently confirm the Israeli claims, and the strikes could also have ignited fuel, cooking gas canisters or other materials in the camp.

The strikes followed earlier Israeli attacks on other parts of the Gaza Strip that killed eight people, four of them children, according to Palestinian medics. The military said it had struck “terrorist targets” in a series of strikes.

On Wednesday, Israel said its forces recovered the body of one hostage who was captured alive during Hamas’ October 7 2023 attack that sparked the war, yet who Israel believes was killed by his captors.